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In the mid-20th century, P. knowlesi became popular as a tool for studying Plasmodium biology and was used for basic research, vaccine research, and drug development. P. knowlesi is still used as a laboratory model for malaria, as it readily infects the model primate the rhesus macaque, and can be grown in cell culture in human or macaque blood.
The Malaria Research Project was primarily conducted on a floor of the prison hospital in the Stateville Penitentiary. The study aimed to understand the effect of various antimalarial drugs on relapses of malaria, primarily from the 8-aminoquinoline group of compounds. The study marked the first human test of the antimalarial drug primaquine. [6]
Reducing the number of mosquitoes that can transmit the malaria parasite would lead to fewer malaria infections. The project’s novel genetic approach aims to be complementary to existing malaria control interventions. The project’s research is still at an early stage, and even though results so far have been promising, there is a long way ...
In 1880, Alphonse Laveran discovered that the causative agent of malaria is a parasite. [2] Detailed work of Golgi in 1886 demonstrated that in some patients there was a relationship between the 72-hour life cycle of the parasite and the chill and fever patterns in the patient. [2] The same observation was found for parasites with 48-hour ...
Malaria is a mosquito-borne infectious disease that affects vertebrates and Anopheles mosquitoes. [6] [7] [3] Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. [1] [8] In severe cases, it can cause jaundice, seizures, coma, or death.
The logo of the Drugs for Neglected Diseases initiative (DNDi) The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients' needs-driven, non-profit drug research and development (R&D) organization that is developing new treatments for neglected diseases, notably leishmaniasis, sleeping sickness (human African trypanosomiasis, HAT), Chagas disease, [1] malaria, filarial ...
The Malaria Journal is a peer-reviewed open access medical journal published by BioMed Central. It was established in 2002 [ 1 ] and covers research on malaria and related topics. The editor-in-chief is Marcel Hommel ( University of Liverpool ).
The Malaria Atlas Project (MAP) is a nonprofit academic group led by Peter Gething, Kerry M Stokes Chair in Child Health, at the Telethon Kids Institute, Perth, Western Australia. The group is funded by the Bill and Melinda Gates Foundation , with previous funding also coming from the Medical Research Council and the Wellcome Trust .