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People with type 1 diabetes mellitus who must take insulin in full replacement doses are most vulnerable to episodes of hypoglycemia (low blood glucose levels). This can occur if a person takes too much insulin or diabetic medication, does strenuous exercise without eating additional food, misses meals, consumes too much alcohol, or consumes alcohol without food. [5]
Stupor, coma, abnormal breathing; Generalized or focal seizures; Plasma glucose 20 mg/dL (1.1 mmol/L) or lower [4] [5] [6] Not all of the above manifestations occur in every case of hypoglycemia. There is no consistent order to the appearance of the symptoms. Specific manifestations vary by age and by the severity of the hypoglycemia.
Diabetic hypoglycemia can be mild, recognized easily by the patient, and reversed with a small amount of carbohydrates eaten or drunk, or it may be severe enough to cause unconsciousness requiring intravenous dextrose or an injection of glucagon. Severe hypoglycemic unconsciousness is one form of diabetic coma. A common medical definition of ...
Manifestations of hyperinsulinemic hypoglycemia vary by age and severity of the hypoglycemia. In general, most signs and symptoms can be attributed to (1) the effects on the brain of insufficient glucose (neuroglycopenia) or (2) to the adrenergic response of the autonomic nervous system to hypoglycemia. A few miscellaneous symptoms are harder ...
Hypoglycemia [citation needed] ... hypoglycemic coma, acute adrenocortical insufficiency, ... List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic ...
In type 1 diabetics, 6–10% will die of hypoglycemia. [ 3 ] Hypoglycemia ( American English ), also spelled hypoglycaemia or hypoglycæmia ( British English ), sometimes called low blood sugar , is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L).
Ketotic hypoglycemia classically presents in male young children, typically between the ages of 10 months and 6 years, in the morning after a prolonged overnight fast. Symptoms include those of neuroglycopenia, ketosis, or both. [6] [7] Neuroglycopenic symptoms usually include lethargy and malaise, but may include unresponsiveness or seizures.
Severe: pH below 7.00, bicarbonate below 10, stupor or coma may occur A 2004 statement by the European Society for Paediatric Endocrinology and the Lawson Wilkins Pediatric Endocrine Society (for children) uses slightly different cutoffs, where mild DKA is defined by pH 7.20–7.30 (bicarbonate 10–15 mmol/L), moderate DKA by pH 7.1–7.2 ...