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Brand named as Phenergan with Codeine or in generic form as promethazine with Codeine, it began to be mixed with soft drinks in the 1990s as a recreational drug, called 'syrup', 'lean', or 'purple drank'. [63] Rapper Pimp C, from the group UGK, died from an overdose of this combination. [64] Codeine is used in illegal drug laboratories to make ...
Respiratory depression is a potentially serious or fatal adverse drug reaction associated with the use of codeine, but mainly the danger lies in the much more potent and CNS-depressing phenothiazine-related antihistamine promethazine. This depression is dose-related and is the mechanism for the potentially fatal consequences of overdose ...
Wockhardt is known for producing cough syrup with the sedative promethazine and the opiate codeine, used in the recreational street drug lean, which is sometimes referred to as "Wock", short for Wockhardt. [21]
Promethazine is preferred during pregnancy because it is an older drug and there is more data regarding the use of it during pregnancy. Second-choice medications, which are used if Promethazine isn't tolerated or the patient cannot take it, are metoclopramide or prochlorperazine .
The medicine has been reclassified by the Medicines and Healthcare products Regulatory Agency.
Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.
Rapper NBA YoungBoy dodges jail time after he pleads guilty to multiple charges tied to his role in a large-scale prescription drug ... for promethazine with codeine — a controlled substance ...
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