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Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
Hypovitaminosis D has been associated with many neurological conditions. However, an actual mechanism of action for each of the conditions has yet to be solidified. Many researchers have questioned whether the depletion of vitamin D actually causes these disorders or if vitamin D deficiency is a symptom of these disorders. [medical citation needed]
A lack of exposure to sunlight, the natural process of aging, and high levels of body fat can all contribute to vitamin D deficiency, which can lead to osteoporosis, bone and joint pain, and ...
The impairment of bone metabolism causes inadequate bone mineralization. Osteomalacia in children is known as rickets, and because of this, use of the term "osteomalacia" is often restricted to the milder, adult form of the disease. Signs and symptoms can include diffuse body pains, muscle weakness, and fragility of the bones.
Maternal vitamin D deficiency can cause fetal bone defects from before birth and impairment of bone quality after birth. [84] [85] Rickets typically appear between 3 and 18 months of age. [86] This condition can be caused by vitamin D, calcium or phosphorus deficiency. [87]
Any child whose diet does not contain enough vitamin D or calcium; Diseases causing soft bones in infants, like hypophosphatasia or hypophosphatemia, can also lead to rickets. [27] Strontium is allied with calcium uptake into bones; at excessive dietary levels strontium has a rachitogenic (rickets-producing) action. [28]