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Zombie cells are thought to build up in all manner of tissues, but they don’t seem to necessarily behave the same way in one part of the body that they do in another.
The liver and kidney are naturally capable of detox, as are intracellular (specifically, inner membrane of mitochondria or in the endoplasmic reticulum of cells) proteins such as CYP enzymes. In cases of kidney failure , the action of the kidneys is mimicked by dialysis ; kidney and liver transplants are also used for kidney and liver failure ...
The chemicals used to kill and remove the cells include acids, alkaline treatments, ionic detergents, non-ionic detergents, and zwitterionic detergents. [ citation needed ] The ionic detergent, sodium dodecyl sulfate (SDS), is commonly used because of its high efficacy for lysing cells without significant damage to the ECM.
Possible senolytic agents are under preliminary research, including some which are in early-stage human trials. [6] [7] [clarification needed] The majority of candidate senolytic compounds are repurposed anti-cancer molecules, such as the chemotherapeutic drug dasatinib and the experimental small molecule navitoclax.
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Natural killer cells (NK cells) and macrophages play a major role in clearance of senescent cells. [65] Natural killer cells directly kill senescent cells, and produce cytokines which activate macrophages which remove senescent cells. [65] Senescent cells can be phagocytized by neutrophils as well as by macrophages. [66]
As they build up in your body, studies suggest, they promote aging and the conditions that come with it like osteoporosis and Alzheimer's disease. Basically the goal is to fight aging itself ...