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  2. Felty's syndrome - Wikipedia

    en.wikipedia.org/wiki/Felty's_syndrome

    The spleen is a lymphatic organ, which means it is largely involved in the immune system and immune responses. When the spleen becomes enlarged, it is a strong sign of infection somewhere in the body and can be caused by inflammatory conditions such as rheumatoid arthritis.

  3. Rheumatoid arthritis - Wikipedia

    en.wikipedia.org/wiki/Rheumatoid_arthritis

    Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]

  4. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  5. Lymphadenopathy - Wikipedia

    en.wikipedia.org/wiki/Lymphadenopathy

    Autoimmune: systemic lupus erythematosus [19] and rheumatoid arthritis may have a generalized lymphadenopathy. [9] Immunocompromised: AIDS. Generalized lymphadenopathy is an early sign of infection with human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). [20] "

  6. Juvenile idiopathic arthritis - Wikipedia

    en.wikipedia.org/wiki/Juvenile_idiopathic_arthritis

    Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (JRA), [1] is the most common chronic rheumatic disease of childhood, affecting approximately 3.8 to 400 out of 100,000 children. [3]

  7. Schnitzler syndrome - Wikipedia

    en.wikipedia.org/wiki/Schnitzler_syndrome

    The Lipsker criteria require hives, the presence of monoclonal IgM, and at least 2 of the following: fever, joint pain or arthritis, bone pain, swollen lymph nodes, enlarged spleen or liver, elevated erythrocyte sedimentation rate, high levels of white blood cells, and findings of problems in bone imaging. [1] [4]

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