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2. Site-directed mutagenesis - Wikipedia

   en.wikipedia.org/wiki/Site-directed_mutagenesis

   Site-directed mutagenesis is used to generate mutations that may produce a rationally designed protein that has improved or special properties (i.e.protein engineering). Investigative tools – specific mutations in DNA allow the function and properties of a DNA sequence or a protein to be investigated in a rational approach. Furthermore ...

3. Sipuleucel-T - Wikipedia

   en.wikipedia.org/wiki/Sipuleucel-T

   As of August 2014, a clinical trial administering sipuleucel-T in conjunction with ipilimumab (Yervoy) was tracking subjects but no longer enrolling new subjects; the trial evaluates the clinical safety and anti-cancer effects (quantified in PSA, radiographic and T cell response) of the combination therapy in patients with advanced prostate cancer.

4. Management of prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Management_of_prostate_cancer

   Surgical removal of the prostate, or prostatectomy, is a common treatment either for early-stage prostate cancer or for cancer that has failed to respond to radiation therapy. The most common type is radical retropubic prostatectomy , when the surgeon removes the prostate through an abdominal incision.

5. Mutagenesis (molecular biology technique) - Wikipedia

   en.wikipedia.org/wiki/Mutagenesis_(molecular...

   Types of mutations that can be introduced by random, site-directed, combinatorial, or insertional mutagenesis. In molecular biology, mutagenesis is an important laboratory technique whereby DNA mutations are deliberately engineered to produce libraries of mutant genes, proteins, strains of bacteria, or other genetically modified organisms.

6. Brachytherapy - Wikipedia

   en.wikipedia.org/wiki/Brachytherapy

   Body sites in which brachytherapy can be used to treat cancer. Brachytherapy is commonly used to treat cancers of the cervix, prostate, breast, and skin. [1]Brachytherapy can also be used in the treatment of tumours of the brain, eye, head and neck region (lip, floor of mouth, tongue, nasopharynx and oropharynx), [10] respiratory tract (trachea and bronchi), digestive tract (oesophagus, gall ...

7. PTEN (gene) - Wikipedia

   en.wikipedia.org/wiki/PTEN_(gene)

   Mutations of this gene are a step in the development of many cancers, specifically glioblastoma, lung cancer, breast cancer, and prostate cancer. Genes corresponding to PTEN ( orthologs ) [ 7 ] have been identified in most mammals for which complete genome data are available.