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Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
The Montgomery–Åsberg Depression Rating Scale (MADRS) is a ten-item [1] diagnostic questionnaire which mental health professionals use to measure the severity of depressive episodes in patients with mood disorders.
Some depression rating scales are completed by patients. The Beck Depression Inventory, for example, is a 21-question self-report inventory that covers symptoms such as irritability, fatigue, weight loss, lack of interest in sex, and feelings of guilt, hopelessness or fear of being punished. [11]
The source for the data below is the OECD Health Statistics 2018, released by the OECD in June 2018 and updated on 8 November 2018. [1]The unit of measurement used by the OECD is defined daily dose (DDD), defined as "the assumed average maintenance dose per day for a drug used on its main indication in adults". [2]
"The Hamilton Rating Scale for Depression" (PDF). Archived from the original (PDF) on 2007-11-20 (49.0 KB) Clinically Useful Psychiatric Scales: HAM-D (Hamilton Depression Rating Scale). Accessed March 6, 2009. Hamilton Depression Rating Scale - Original scientific paper published in 1960 in Psychiatry out of Print website. Accessed June 27, 2008.
As an example, the escitalopram article would have the Antidepressants/SSRI template, as well as the Antidepressants template, on it, giving the user one box with a list of the types of antidepressants covered on WP, and another box with a list of SSRIs. Zuiram 03:30, 30 October 2006 (UTC)
A number of researchers have explored HADS data to establish the cut-off points for caseness of anxiety or depression. Bjelland et al (2002) [3] through a literature review of a large number of studies identified a cut-off point of 8/21 for anxiety or depression. For anxiety (HADS-A) this gave a specificity of 0.78 and a sensitivity of 0.9.
According to National Institute for Health and Care Excellence (NICE) guidelines, antidepressants for children and adolescents with depression and obsessive-compulsive disorder (OCD) should be prescribed together with therapy and after being assessed by a child and adolescent psychiatrist. However, between 2006 and 2017, only 1 in 4 of 12–17 ...