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Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. [5][6] It occurs most frequently in people in their teens and twenties but is also common among the elderly. It can be caused by heredity, immune disease, or exposure to chemicals, drugs, or radiation.
Pure red cell aplasia affects the red blood cells in particular. Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of aplastic anemia affecting the precursors to red blood cells but usually not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA.
Aplasia (/ əˈpleɪʒə / ⓘ; from Greek a, "not", "no" + plasis, "formation") is a birth defect where an organ or tissue is wholly or largely absent. It is caused by a defect in a developmental process. [1][2] Aplastic anemia is the failure of the body to produce blood cells.
Aplastic anemia [31] affects all kinds of blood cells. Fanconi anemia is a hereditary disorder or defect featuring aplastic anemia and various other abnormalities. Anemia of kidney failure [31] due to insufficient production of the hormone erythropoietin; Anemia of endocrine disease [32] Disturbance of proliferation and maturation of erythroblasts
Hematology. Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. [3] DBA causes low red blood cell counts (anemia), without substantially affecting the other blood components (the platelets and the white blood cells), which are usually normal. This is in contrast to Shwachman–Bodian–Diamond ...
Aplastic Anemia. Reticulocytopenia is the medical term for an abnormal decrease in circulating red blood cell precursors (reticulocytes) that can lead to anemia due to resulting low red blood cell (erythrocyte) production. [1] Reticulocytopenia may be an isolated finding or it may not be associated with abnormalities in other hematopoietic cell ...
Anemia of chronic disease, hereditary spherocytosis, acute blood loss, aplastic anemia (anemia resulting from an inability of the bone marrow to produce red blood cells), and certain hereditary hemoglobinopathies (including some cases of thalassemia minor) may all present with a normal RDW.
54,200 (2015) [7] Iron-deficiency anemia is anemia caused by a lack of iron. [3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [1]