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Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development.
The polypeptide hormone IGF-1 is synthesized primarily in the liver upon stimulation by growth hormone (GH). It is a key mediator of anabolic activities in numerous tissues and cells, such as growth hormone-stimulated growth, metabolism and protein translation. [17]
Growth hormone 1, also known as pituitary growth hormone or simply as growth hormone (GH) somatotropin, is a protein that in humans is encoded by the GH1 gene. [ 5 ] The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
1944 - Li was the first person to isolate growth hormone from cow brains. [8] The lack of function of cow growth hormone on human body motivated Dr. Li to find human growth hormone. 1956 - Li successfully isolated human and monkey growth hormone and demonstrated its efficacy to treat hypopituitary children. [9]
Insulin-like growth factor 1 (commonly referred to as IGF-1 or at times using Roman numerals as IGF-I) is mainly secreted by the liver as a result of stimulation by growth hormone (GH). IGF-1 is important for both the regulation of normal physiology, as well as a number of pathological states, including cancer .
Production of a single year's supply of human growth hormone required up to fifty pituitary glands, [3] creating significant shortages of the hormone. [4] In 1979, scientists at Genentech produced human growth hormone by inserting DNA coding for human growth hormone into a plasmid that was implanted in Escherichia coli bacteria.
For more information, patients treated with cadaver-derived human growth hormone in the U.S. can call the National Institute of Diabetes and Digestive and Kidney Diseases at 1-800-860-8747 or ...
Growth hormone–releasing hormone (GHRH), also known as somatocrinin among other names in its endogenous form and as somatorelin in its pharmaceutical form, is a releasing hormone of growth hormone (GH). It is a 44 [1]-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus.
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