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Perichondrium can be found around the perimeter of elastic cartilage and hyaline cartilage. Perichondrium is a type of irregular collagenous ordinary connective tissue, and also functions in the growth and repair of cartilage. Perichondrium contains type I collagen [1] and type XII collagen. [2]
A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele
Endochondral ossification is the process by which most vertebrate axial skeletons form into hardened bones from cartilage. This process begins with a cartilage anlage where chondrocyte cells will congregate and start their maturation process. Once the chondrocytes have fully matured at the desired rate, the cartilage tissue will harden into ...
Within adults and developing adults, most chondroblasts are located in the perichondrium. This is a thin layer of connective tissue which protects cartilage and is where chondroblasts help to expand cartilage size whenever prompted to by hormones such as GH, TH, and glycosaminoglycans. [2]
Hyaline cartilage has fewer cells than elastic cartilage; there is more intercellular space. Hyaline cartilage is found in the nose, ears, trachea, parts of the larynx, and smaller respiratory tubes. Fibrous cartilage has the fewest cells so it has the most intercellular space. Fibrous cartilage is found in the spine and the menisci.
This hyaline cartilage template expands through both: [8] [9] Interstitial growth Appositional growth Cellular protagonists: Chondrocytes present within the existing cartilage. Chondroblasts that develop from the perichondrium. Mechanism: Chondrocytes proliferate and lay down matrix. Chondroblasts differentiate into chondrocytes and lay down ...
In cartilage, the lacunae and hence, the chondrocytes, are isolated from each other. Materials picked up by osteocytes adjacent to blood vessels are distributed throughout the bone matrix via the canaliculi. Diameter of canaliculi in human bone is approximately 200 to 900 nm. [1]
Studies have shown that embryonic stem cells are more mechanosensitive than their differentiated counterparts. During embryonic development mesenchymal cells will form cellular structures known as 'condensations.' These cellular units will then develop into skeletal and other tissues, such as cartilage, tendon, ligament and muscle tissue.