Ads
related to: does d3 affect kidneys- Recommended Dosage
Discover Appropriate Dosage
to Treat Patients
- Medical Experts
Watch Healthcare Professionals
Share Transplant Insights
- Kidney Transplant
Treatment for Kidney
Transplant Immunosuppression
- Storage & Handling
Learn to Properly Store and
Handle Treatment for Patients
- Recipients
Discover How Patients
May Benefit from Treatment
- Kidney Transplant Therapy
Read About How Treatment May
Fight Against Acute Rejection
- Recommended Dosage
Search results
Results From The WOW.Com Content Network
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
A third important effect of PTH on the kidneys is stimulation of the conversion of 25-hydroxy vitamin D into 1,25-dihydroxy vitamin D (calcitriol). [216] This form of vitamin D is the active hormone which promotes calcium uptake from the intestine via the action of calbindin . [ 218 ]
Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]
Certain conditions can affect the body's ability to synthesize or absorb vitamin D, such as liver disease, kidney disease and inflammatory bowel disease, Adamian adds.
Osteoporosis, osteomalacia and rickets are bone disorders linked to calcium metabolism disorders and effects of vitamin D. Renal osteodystrophy is a consequence of chronic kidney failure related to the calcium metabolism. A diet adequately rich in calcium may reduce calcium loss from bone with advancing (post-menopausal) age. [30]
Researchers believe there may be a link between long-term vitamin D deficiency and the development of autoimmune conditions, such as type 1 diabetes and rheumatoid arthritis, but more research is ...
Ads
related to: does d3 affect kidneys