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Original file (975 × 1,462 pixels, file size: 2.71 MB, MIME type: application/pdf, 194 pages) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
Crash Course Manual was edited by Doug Kaufman, with a cover by Robert Larkin, and was published by West End Games in 1990 as a 96-page book. [2]Shannon Appelcline commented that metaplots for Paranoia "kicked off with the 'Secret Society Wars' in The DOA Sector Travelogue (1989), which seemed OK, but then things took a dramatic wrong turn with Crash Course Manual (1989), which introduced ...
Translation promotes transcription elongation and regulates transcription termination. Functional coupling between transcription and translation is caused by direct physical interactions between the ribosome and RNA polymerase ("expressome complex"), ribosome-dependent changes to nascent mRNA secondary structure which affect RNA polymerase activity (e.g. "attenuation"), and ribosome-dependent ...
The process of transcription is a major source of DNA damage, due to the formation of single-strand DNA intermediates that are vulnerable to damage. [53] The regulation of transcription by processes using base excision repair and/or topoisomerases to cut and remodel the genome also increases the vulnerability of DNA to damage. [53]
A eukaryotic cell has a nucleus that separates the processes of transcription and translation. Eukaryotic transcription occurs within the nucleus where DNA is packaged into nucleosomes and higher order chromatin structures. The complexity of the eukaryotic genome necessitates a great variety and complexity of gene expression control. Eukaryotic ...
The transcription-translation process description, mentioning only the most basic "elementary" processes, consists of: production of mRNA molecules (including splicing), initiation of these molecules with help of initiation factors (e.g., the initiation can include the circularization step though it is not universally required),