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A 2019 study suggested that oral B 12 is inferior to B 12 injections in severe cases, as "there is no proof in large prospective, double-blind studies that oral supplementation is as effective in reducing symptoms associated with vitamin B 12 deficiency as parenteral treatment." [153] There is risk that folic acid administered to those with ...
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
Thus all of the DNA synthetic effects of B 12 deficiency, including the megaloblastic anemia of pernicious anemia, resolve if sufficient dietary folate is present. Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an ...
As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. [1] [2] Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. [3] [4] It is given by injection into a muscle or vein, [2] by pill or sublingually. Side effects are generally few. [2]
Folate in the form of folic acid is used to treat anemia caused by folate deficiency. [3] Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. [3] [10] NTDs include anencephaly and spina bifida, among other defects.
It has been proved to prevent serious birth defects of a baby’s brain and spine, and since the benefits of folic acid are most pivotal in the early days and weeks of a fetus’s development ...