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Vagusstoff (literally translated from German as "Vagus Substance") refers to the substance released by stimulation of the vagus nerve which causes a reduction in the heart rate. Discovered in 1921 by physiologist Otto Loewi , vagusstoff was the first confirmation of chemical synaptic transmission and the first neurotransmitter ever discovered.
His experiment was iconic because it was the first to demonstrate the endogenous release of a chemical substance that could cause a response in the absence of electrical stimulation. It paved the way for the understanding that the electrical signaling event (action potential) causes a chemical event (release of neurotransmitter from synapses ...
Sample_data_from_an_EDXRD_experiment.pdf (525 × 316 pixels, file size: 204 KB, MIME type: application/pdf) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
Vagusstoff transmitted inhibition from the vagus nerves, and Acceleransstoff transmitted stimulation from the sympathetic nerves to the heart. [31] Loewi took some years to commit himself with respect to the nature of the Stoffe , but in 1926 he was sure that Vagusstoff was acetylcholine, writing in 1936 [ 32 ] "I no longer hesitate to identify ...
Lab notebook with the complete record of the experiments underlying a published paper. [1] Chemistry stencils that used to be used for drawing equipment in lab notebooks. A laboratory notebook ( colloq. lab notebook or lab book ) is a primary record of research .
An SDRF file is a tab-delimited file describing the relationships between samples, arrays, data, and other objects used or produced in a microarray investigation. For simple experimental designs, constructing the SDRF file is straightforward, and even complex loop designs can be expressed in this format.
Variety of microbiological samples. A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment.
Example of an approximately 40,000 probe spotted oligo microarray with enlarged inset to show detail. Microarray analysis techniques are used in interpreting the data generated from experiments on DNA (Gene chip analysis), RNA, and protein microarrays, which allow researchers to investigate the expression state of a large number of genes – in many cases, an organism's entire genome – in a ...