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In the lab, phenyl-2-nitropropene is produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst like n-butylamine.The reaction is a nitroaldol reaction, and is a variant of a Knoevenagel condensation reaction, which is one of a broader class of reactions called Henry condensations, or simply Henry reactions.
2-bromo-1-phenylpentan-1-one substituted cathinones and substituted amphetamines: 2-bromo-1-phenylpropan-1-one substituted cathinones and substituted amphetamines: BMK glycidic acid and esters methamphetamine 3-oxo-2-phenylbutanoic acid and its esters methamphetamine 3,4-methylenedioxyphenyl-2-nitropropene (MDP2NP) MDMA: Ammonia gas
Via condensations like the Henry reaction, nitroethane converts to several compounds of commercial interest.Condensation with 3,4-dimethoxybenzaldehyde affords the precursor to the antihypertensive drug methyldopa; condensation with unsubstituted benzaldehyde yields phenyl-2-nitropropene, a precursor for amphetamine drugs.
Phenylpropenes broadly are compounds containing a phenyl ring bonded to propene, more specifically those with an allyl group bonded to a benzene ring, having the parent structure of allylbenzene. These comprise a class of phenylpropanoids , where there are typically other substituents bonded to the aromatic ring.
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Phenylacetones are a group of organic compounds containing a phenyl moiety and an acetone moiety bonded together, the archetypal example being phenylacetone.. Phenylacetones often play a role in the illicit synthesis of amphetamine and its analogues, 3,4-methylenedioxyphenyl-2-propanone (MDP2P) for example being used in the production of 3,4-methylenedioxyamphetamine (MDA), [1] 3,4 ...
This category includes chemical compounds that include a phenyl group, C 6 H 5 –. (That is, benzene with only one substituent or bond.) For benzene derivatives ( derivatives or structural analogs of benzene ) in which benzene has multiple substituents or bonds, see the parent category, Category:Benzene derivatives .