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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    A prolonged-release 2 mg oral formulation of melatonin sold under the brand name Circadin is approved for use in the European Union in the short-term treatment of insomnia in people age 55 and older. [11] [29] [8] Melatonin is also available as an over-the-counter dietary supplement in many countries. It is available in both immediate-release ...

  3. 5 symptoms women over 40 should always take seriously - AOL

    www.aol.com/finance/5-symptoms-women-over-40...

    The study, which involved 106 peri- and postmenopausal women and was presented at the Endocrine Society’s annual meeting in May, indicates women should self-monitor their vasomotor symptoms and ...

  4. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Individuals who have had more withdrawal episodes are at an increased risk of very severe withdrawal symptoms, up to and including seizures and death. Long-term activation of the GABA receptor by sedative–hypnotic drugs causes chronic GABA receptor downregulation as well as glutamate overactivity, which can lead to drug and neurotransmitter ...

  5. Delayed sleep phase disorder - Wikipedia

    en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

    Good effect was seen during the six-week treatment with a large daily dose of melatonin. After ceasing melatonin use over 90% had relapsed to pre-treatment sleeping patterns within the year, 29% reporting that the relapse occurred within one week. The mild cases retained changes significantly longer than the severe cases. [53]

  6. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  7. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    Treatment for withdrawal usually involves weaning over a 3- to 21-day period if the infusion lasted for more than a week. [134] Symptoms include tremors, agitation, sleeplessness, inconsolable crying, diarrhea and sweating. In total, over fifty withdrawal symptoms are listed in this review article.

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