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Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
Codocytes, also known as target cells, are red blood cells that have the appearance of a shooting target with a bullseye. In optical microscopy these cells appear to have a dark center (a central, hemoglobinized area) surrounded by a white ring (an area of relative pallor), followed by dark outer (peripheral) second ring containing a band of ...
Basophilic is a technical term used by pathologists. It describes the appearance of cells , tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye .
Basophilic stippling is one morphologic finding of thalassemia which does not appear in iron deficiency or anemia of chronic disease. The patient should be in an ethnically at-risk group and the diagnosis is not confirmed without a confirmatory method such as hemoglobin HPLC, H body staining, molecular testing or another reliable method.
Basophilic stippling is marked and target cells are common. The mean cell volume is commonly decreased (i.e., a microcytic anemia), but it may also be normal or even high. The RDW is increased with the red blood cell histogram shifted to the left. Leukocytes and platelets are normal. Bone marrow shows erythroid hyperplasia with a maturation ...
Here’s what you need to know about this common condition. Can you fully recover from botulism? When botulism is left untreated, your body enters a state of complete respiratory paralysis ...
While Marburg virus isn’t well-known to most Americans, Dr. Russo points out that it’s a “cousin of Ebola.” Marburg virus is most commonly found in sub-Saharan Africa, per the CDC.
Mast cells were once thought to be basophils that migrated from the blood into their resident tissues (connective tissue), but they are now known to be different types of cells. [ 5 ] Basophils were discovered in 1879 by German physician Paul Ehrlich , who one year earlier had found a cell type present in tissues that he termed mastzellen (now ...