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Some drugs need to be used with caution in patients with renal dysfunction. The use of nitrofurantoin is contraindicated in patients with an estimated GFR of less than 30 mL/min/1.73m 2 as drug accumulation can lead to increased side effects and impaired recovery of the urinary tract, increasing the risk of treatment failure. [29]
Nitrofurantoin, sold under the brand name Macrobid among others, is an antibacterial medication of the nitrofuran class used to treat urinary tract infections (UTIs), although it is not as effective for kidney infections. [16] It is taken by mouth. [16] Common side effects include nausea, loss of appetite, diarrhea, and headaches. [16]
Pentosan polysulfate, sold under the brand name Elmiron among others, is a medication used for the treatment of interstitial cystitis. [1] It was approved for medical use in the United States in 1996. [1] [2] [3]
Cystitis—Comprehensive overview covers symptoms, causes, treatment, prevention of bladder inflammation.
Women with recurrent simple UTIs are over 90% accurate in identifying new infections. [4] They may benefit from self-treatment upon occurrence of symptoms with medical follow-up only if the initial treatment fails. [4] The combination sulopenem etzadroxil/probenecid (Orlynvah) was approved for medical use in the United States in October 2024 ...
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
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