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Intraperitoneal injection or IP injection is the injection of a substance into the peritoneum (body cavity). It is more often applied to non-human animals than to humans. In general, it is preferred when large amounts of blood replacement fluids are needed or when low blood pressure or other problems prevent the use of a suitable blood vessel for intravenous injection.
The peritoneal cavity is widely used in intraperitoneal injections to administer chemotherapy drugs, [5] [6] and is also utilized in peritoneal dialysis. [7] An increase in capillary pressure in the abdominal organs can cause fluid to leave the interstitial space and enter the peritoneal cavity, resulting in a condition called ascites.
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue.
The interior is called the peritoneal cavity, this is the location of all 'intra-peritoneal' organs (disambiguation: retro-peritoneal organs). The most inferior extent of the peritoneum covers the pelvic inlet; in females, this region of the peritoneum is referred to as the 'broad ligament'.
Peritoneal fluid is a serous fluid made by the peritoneum in the abdominal cavity which lubricates the surface of tissue that lines the abdominal wall and pelvic cavity. It covers most of the organs in the abdomen. An increased volume of peritoneal fluid is called ascites. Sampling of peritoneal fluid is generally performed by paracentesis.
the duodenum, except for the proximal first segment, which is intraperitoneal [4] ascending and descending portions of the colon (but not the transverse colon, sigmoid and the cecum) pancreas, except for the tail, which is intraperitoneal
Peritoneal dialysis was first carried out in the 1920s; however, long-term use did not come into medical practice until the 1960s. [35] The timeline was 1923 – Georg Ganter performs the first peritoneal dialysis in a guinea pig and attempts the procedure in humans, without success. Hypertonic saline was used as the dialysate. [35] [36]
Pneumoperitoneum is pneumatosis (abnormal presence of air or other gas) in the peritoneal cavity, a potential space within the abdominal cavity.The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.