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  2. Common Rule - Wikipedia

    en.wikipedia.org/wiki/Common_rule

    The Common Rule is a 1991 rule of ethics (revised in 2018) [2] regarding biomedical and behavioral research involving human subjects in the United States.The regulations governing Institutional Review Boards for oversight of human research followed the 1975 revision of the Declaration of Helsinki, and are encapsulated in the 1991 revision to the U.S. Department of Health and Human Services ...

  3. Human subject research - Wikipedia

    en.wikipedia.org/wiki/Human_subject_research

    The Common Rule, first published in 1991, also known as the Federal Policy for the Protection of Human Subjects, [7] is dictated by the Office of Human Research Protections under the United States Department of Health and Human Services and serves as a set of guidelines for institutional review boards (IRBs), obtaining informed consent, and ...

  4. Guidelines for human subject research - Wikipedia

    en.wikipedia.org/wiki/Guidelines_for_human...

    Subsequently, the National Research Act of 1974 led to the creation of the Common Rule, the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, and the Office for Human Research Protections. All of these reactions led to the 1979 creation and publishing of the Belmont Report.

  5. Human subject research legislation in the United States

    en.wikipedia.org/wiki/Human_subject_research...

    [6] [7] [8] Beecher's study listed over 20 cases of mainstream research where subjects were subject to experimentation without being fully informed of their status as research subjects, and without knowledge of the risks of such participation in the research. Some of the research subjects died or were permanently crippled as a result of that ...

  6. Belmont Report - Wikipedia

    en.wikipedia.org/wiki/Belmont_Report

    The Belmont Report is a 1978 report created by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.Its full title is the Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research, Report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.

  7. Nuremberg Code - Wikipedia

    en.wikipedia.org/wiki/Nuremberg_Code

    In the United States, the Code and the related Declaration of Helsinki influenced the drafting of regulations promulgated by the United States Department of Health and Human Services to ensure ethical treatment of human research subjects, known as the Common Rule, which is now codified in Part 46 of Title 45 of the Code of Federal Regulations.

  8. Office for Human Research Protections - Wikipedia

    en.wikipedia.org/wiki/Office_for_Human_Research...

    The Office for Human Research Protections (OHRP) is a small office within the United States Department of Health and Human Services (DHHS), specifically the Office of the Assistant Secretary for Health in the Office of the Secretary of DHHS, that deals with ethical oversights in clinical research conducted by the department, mostly through the National Institutes of Health (NIH).

  9. Unethical human experimentation in the United States

    en.wikipedia.org/wiki/Unethical_human...

    A subject of the Tuskegee syphilis experiment has his blood drawn, c. 1953.. Numerous experiments which were performed on human test subjects in the United States in the past are now considered to have been unethical, because they were performed without the knowledge or informed consent of the test subjects. [1]