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The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called CC chemokine ligands -1 to -28; CCL10 is the same as CCL9. Chemokines of this subfamily usually contain four cysteines (C4-CC chemokines ...
CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins since they span the cell membrane seven times.
The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2.CCL2 is a small cytokine that belongs to the CC chemokine family.
C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. [5] CCR2 is a CC chemokine receptor . Gene
Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. [5] CCR6 has also recently been designated CD196 (cluster of differentiation 196). The gene is located on the long arm of Chromosome 6 (6q27) on the Watson (plus) strand.
1230 12768 Ensembl ENSG00000163823 ENSMUSG00000025804 UniProt P32246 P51675 RefSeq (mRNA) NM_001295 NM_009912 RefSeq (protein) NP_001286 NP_034042 Location (UCSC) Chr 3: 46.2 – 46.21 Mb Chr 9: 123.76 – 123.77 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. CCR1 has also recently been designated ...
CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans.
The CCR 3 receptor is a CC chemokine receptor that is a 7-transmembrane, G-linked protein receptor. This receptor is primarily found on eosinophils and basophils. The CCR 3 receptor is what regulates the eotaxin's activity. It does this through selective expression. When eotaxin binds with the CCR 3 Receptor, it induces biological changes.