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Syrup of ipecac (/ ˈ ɪ p ɪ k æ k /), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant ( Carapichea ipecacuanha ), from which it derives its name.
Inducing vomiting with syrup of ipecac has no role in paracetamol overdose because the vomiting it induces delays the effective administration of activated charcoal and oral acetylcysteine. [19] Liver injury is extremely rare after acute accidental ingestion in children under 6 years of age.
Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac. [2] Chemically, it is closely related to emetine . Poison treatment
Although this therapy was reportedly successful, the extract caused vomiting in many patients, which reduced its utility. In some cases, it was given with opioids to reduce nausea . Other approaches to reduce nausea involved coated tablets, allowing the drug to be released after digestion in the stomach.
Vomiting is dangerous if gastric content enters the respiratory tract. Under normal circumstances, the gag reflex and coughing prevent this from occurring; however, these protective reflexes are compromised in persons who are under the influence of certain substances (including alcohol) or even mildly anesthetized.
An anion-gap metabolic acidosis occurs later in the course of the overdose, especially if it is a moderate to severe overdose, due to the increase in protons (acidic contents) in the blood. The diagnosis of poisoning usually involves measurement of plasma salicylate, the active metabolite of aspirin, by automated spectrophotometric methods.
Corn syrup explained: The liquid sweetener manages the unlikely feat of being one of the most valuable and most misunderstood ingredients in the kitchen.
Syrup of ipecac, emetic substance often used to induce vomiting Topics referred to by the same term This disambiguation page lists articles associated with the title EPICAC .