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Dutcher and Russell bodies. H&E stain. Russell bodies are inclusion bodies usually found in atypical plasma cells that become known as Mott cells. [1] Russell bodies are eosinophilic, homogeneous immunoglobulin (Ig)-containing inclusions usually found in cells undergoing excessive synthesis of Ig; the Russell body is characteristic of the ...
Plasma cells with Dutcher and Russell bodies (H&E stain, 100×, oil) Plasma cells are large lymphocytes with abundant cytoplasm and a characteristic appearance on light microscopy. They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement.
Being asymptomatic, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma are typically diagnosed fortuitously by detecting a myeloma protein on serum protein electrophoresis tests done for other purposes. MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses ...
Poikilocytosis is variation in the shapes of red blood cells.Poikilocytes may be oval, teardrop-shaped, sickle-shaped or irregularly contracted. Normal red blood cells are round, flattened disks that are thinner in the middle
Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered on a complete blood count by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps due to anisocytosis.
Hypersegmentation can also be seen in many other conditions but with relatively less diagnostic significance. Hypersegmentation can sometimes be difficult to assert since interobserver variation is high and segmentation may vary with race.
Johnson Production Group/Hallmark Christopher Russell landed his first lead role for Hallmark Channel in 2014’s Midnight Masquerade — and he has continued to woo viewers with his movie charm.
A degmacyte or bite cell is an abnormally shaped mature red blood cell with one or more semicircular portions removed from the cell margin, known as "bites". [1] [2] These "bites" result from the mechanical removal of denatured hemoglobin during splenic filtration as red cells attempt to migrate through endothelial slits from splenic cords into the splenic sinuses. [3]