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Depigmentation is the lightening of the skin or loss of pigment. Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1]
In addition to genetic factors, poliosis can develop due to various inflammatory, autoimmune, or neoplastic conditions, or as a side effect of medication.. Vitiligo: This autoimmune disorder leads to the destruction of melanocytes, resulting in depigmented skin patches.
The skin will appear paler than the surrounding skin surface once an injury has healed. [4] Different areas of the skin may be hypopigmented as a result of other genetic illnesses. Hypopigmentation can be caused by hereditary conditions such as vitiligo, melasma, pityriasis versicolor, pityriasis alba, albinism, and fungal infections. [4]
The only sign of vitiligo is the presence of pale patchy areas of depigmented skin which tend to occur on the extremities. [7] [8] Some people may experience itching before a new patch appears. [9] The patches are initially small, but often grow and change shape. [7] [10] When skin lesions occur, they are most prominent on the face, hands and ...
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Alfred Blaschko, a private practice dermatologist from Berlin, first described and drew the patterns of the lines of Blaschko in 1901. He obtained his data by studying over 140 patients with various nevoid and acquired skin diseases and transposed the visible patterns the diseases followed onto dolls and statues, then compiled the patterns onto a composite schematic of the human body.
The best anti-aging serums reduce visible signs of aging like fine lines, wrinkles, and discoloration. Here, dermatologists share the best ones.
To address lines, try a collagen-stimulating retinoid. Topical ingredients that activate estrogen receptors in skin, like methylestradiolpropanoate, or MEP, have been shown in studies to improve ...