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According to the cardiocentric hypothesis, the heart is the primary location of human emotions, cognition, and awareness. [1] This notion may be traced back to ancient civilizations such as Egypt and Greece, where the heart was regarded not only as a physical organ but also as a repository of emotions and wisdom. [2]
Coronal section of inferior horn of lateral ventricle. Fimbria labeled at center left and alveus to the right. Fimbria-fornix fibers are the hippocampal and subicular gateway to and from subcortical brain regions. [10] [11] Different parts of this system are given different names:
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are the components of the hippocampal formation located in the limbic system.
In 1937, Papez theorized that a neural circuit (the Papez circuit) including the hippocampal formation and the cingulate gyrus constitutes the neural substrate of emotional behavior, [3] and Klüver and Bucy reported that, in monkeys, resection involving the hippocampal formation and the amygdaloid complex has a profound effect on emotional ...
It is an integral part of the limbic system, which is involved with emotion formation and processing, [1] learning, [2] and memory. [ 3 ] [ 4 ] The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which ...
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus , the presubiculum , and the subiculum .
Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
The subicular complex receives input from CA1 and entorhinal cortical layer III pyramidal neurons and is the main output of the hippocampus proper.The pyramidal neurons send projections to the nucleus accumbens, septal nuclei, prefrontal cortex, lateral hypothalamus, nucleus reuniens, mammillary nuclei, entorhinal cortex and amygdala.