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  2. Tissue-type plasminogen activator - Wikipedia

    en.wikipedia.org/wiki/Tissue-type_plasminogen...

    However, many patients who were eligible for treatment were not treated. [14] [15] tPA has also been given to patients with acute ischemic stroke above age 90 years old. Although a small fraction of patients 90 years and above treated with tPA for acute ischemic stroke recover, most patients have a poor 30-day functional outcome or die. [16]

  3. Alteplase - Wikipedia

    en.wikipedia.org/wiki/Alteplase

    Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]

  4. Thrombolysis - Wikipedia

    en.wikipedia.org/wiki/Thrombolysis

    Thrombolysis, also called fibrinolytic therapy, is the breakdown of blood clots formed in blood vessels, using medication.It is used in ST elevation myocardial infarction, stroke, and in cases of severe venous thromboembolism (massive pulmonary embolism or extensive deep vein thrombosis).

  5. Lifestyle changes key to preventing strokes, new guidelines ...

    www.aol.com/stroke-prevention-guidelines...

    Latest stroke prevention guidelines highlight the importance of lifestyle interventions for cardiovascular health and managing conditions such as type 2 diabetes and high blood pressure.

  6. National Institutes of Health Stroke Scale - Wikipedia

    en.wikipedia.org/wiki/National_Institutes_of...

    The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...

  7. Reperfusion therapy - Wikipedia

    en.wikipedia.org/wiki/Reperfusion_therapy

    Emergency bypass surgery for the treatment of an acute myocardial infarction (MI) is less common than PCI or thrombolysis. From 1995 to 2004, the percentage of people with cardiogenic shock treated with primary PCI rose from 27.4% to 54.4%, while the increase in coronary artery bypass graft surgery (CABG) was only from 2.1% to 3.2%. [ 34 ]

  8. Hemorrhagic transformation - Wikipedia

    en.wikipedia.org/wiki/Hemorrhagic_transformation

    The risk of HT increases with the severity and duration of the initial stroke, as well as with certain medical conditions such as high blood pressure, diabetes, and clotting disorders [3] and the use of certain medications, such as anticoagulants and thrombolytic tpA medication (such as alteplase) which can increase the bleeding risk. [4] [5]

  9. Cerebral venous sinus thrombosis - Wikipedia

    en.wikipedia.org/wiki/Cerebral_venous_sinus...

    The 2006 European Federation of Neurological Societies guideline recommends that thrombolysis is only used in people who deteriorate despite adequate treatment, and other causes of deterioration have been eliminated. It is unclear which drug and which mode of administration is the most effective.