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Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. [2] This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs , such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small ...
Identification, expression, evolution and function of long non-coding RNAs (LncRNAs), small RNAs and circular RNAs from deep-sequencing data [3] LNCipedia: A comprehensive compendium of human long non-coding RNAs. [4] [5] lncRNAdb: The Reference Database For Functional Long Noncoding RNAs. [6] LncRNAWiki
In bioinformatics, lncRNAdb is a biological database of Long non-coding RNAs [1] [2] The database focuses on those RNAs which have been experimentally characterised with a biological function. The database currently holds over 290 lncRNAs from around 60 species. Example lncRNAs in the database are HOTAIR and Xist. [1] [2]
The transcriptome includes the transcripts of protein-coding genes (mRNA plus introns) as well as the transcripts of non-coding genes (functional RNAs plus introns). Ribosomal RNA/rRNA: Usually the most abundant RNA in the transcriptome. Long non-coding RNA/lncRNA: Non-coding RNA transcripts that are more than 200 nucleotides long. Members of ...
How NORAD works with PUM proteins to contribute to genomic instability. [1]Noncoding RNA Activated by DNA Damage (NORAD) is a long non-coding RNA that responds to DNA damage and plays a significant role in preserving stability (keeping it accurate and unchanged) of genetic information within cells. [2]
The roles of non-coding RNAs: Ribonucleoproteins are shown in red, non-coding RNAs in blue. A non-coding RNA ( ncRNA ) is a functional RNA molecule that is not translated into a protein . The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene .
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These so-called non-coding RNAs ("ncRNA") can be encoded by their own genes (RNA genes), but can also derive from mRNA introns. [32] The most prominent examples of non-coding RNAs are transfer RNA (tRNA) and ribosomal RNA (rRNA), both of which are involved in the process of translation. [7]