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  2. Valve interstitial cells - Wikipedia

    en.wikipedia.org/wiki/Valve_interstitial_cells

    Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.

  3. Cardiac fibrosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_fibrosis

    Interstitial fibrosis, which is unspecific, and has been described in congestive heart failure, hypertension, and normal aging. [2] Subepicardial fibrosis, also unspecific, and is associated with non-infarction diagnoses such as myocarditis and non-ischemic cardiomyopathy. [3] [4] Replacement fibrosis, which indicates an older infarction. [2]

  4. Intercalated disc - Wikipedia

    en.wikipedia.org/wiki/Intercalated_disc

    Mutations in the intercalated disc gene are responsible for various cardiomyopathies that can lead to heart failure. [2] Ruptured intercalated discs, in this case regarded as a visual artifact. Ruptured intercalated discs, when seen on histopathology, have two main causes: Microtome sectioning, thereby being a visual artifact. [4]

  5. Interstitium - Wikipedia

    en.wikipedia.org/wiki/Interstitium

    The composition and chemical properties of the interstitial fluid vary among organs and undergo changes in chemical composition during normal function, as well as during body growth, conditions of inflammation, and development of diseases, [2] as in heart failure [5] and chronic kidney disease. [6]

  6. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.

  7. Heart valve - Wikipedia

    en.wikipedia.org/wiki/Heart_valve

    A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Heart valves are opened or closed by a difference in blood pressure on each side. [1] [2] [3]