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Myasthenia gravis (MG) is a long-term neuromuscular junction disease that leads to varying degrees of skeletal muscle weakness. [1] The most commonly affected muscles are those of the eyes, face, and swallowing. [1][5] It can result in double vision, drooping eyelids, and difficulties in talking and walking. [1]
C2310H3554N602O692S14. Molar mass. 51 280.20 g·mol −1. Efgartigimod alfa, sold under the brand name Vyvgart, is a medication used to treat myasthenia gravis. [3][4] Efgartigimod alfa is a neonatal Fc receptor blocker and is a new class of medication. [4] It is an antibody fragment that binds to the neonatal Fc receptor (FcRn), preventing ...
The company is testing its drug, inebilizumab or Uplizna, in patients suffering from myasthenia gravis, which is caused by an abnormal immune reaction that weakens the muscles that control the ...
Rare. Transient neonatal myasthenia gravis, i.e., TNMG (also termed neonatal myasthenia gravis [1]), and its more severe form, fetal acetylcholine receptor inactivation syndrome (i.e., FARIS), is one of the various types of myasthenia gravis (i.e., MG). [2] MG is an autoimmune disease in which individuals form antibodies that circulate in their ...
Ocular myasthenia gravis (MG) is a disease of the neuromuscular junction resulting in hallmark variability in muscle weakness and fatigability. MG is an autoimmune disease where anomalous antibodies are produced against the naturally occurring acetylcholine receptors in voluntary muscles. MG may be limited to the muscles of the eye (ocular MG ...
In myasthenia gravis, there is a variable weakness of skeletal muscles, which is exacerbated by repeated contraction. To cause sustained contraction of levator palpebrae superioris muscle, the patient is asked to gaze upward for an extended period of time, without lifting the head.
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