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The Wood–Ljungdahl pathway is a set of biochemical reactions used by some bacteria. It is also known as the reductive acetyl-coenzyme A ( acetyl-CoA ) pathway . [ 1 ] This pathway enables these organisms to use hydrogen ( H 2 ) as an electron donor , and carbon dioxide (CO 2 ) as an electron acceptor and as a building block to generate ...
The pathway is antagonized by various factors including PTEN, [7] GSK3B, [2] and HB9. [5] In many cancers, this pathway is overactive, thus reducing apoptosis and allowing proliferation. This pathway is necessary, however, to promote growth and proliferation over differentiation of adult stem cells, neural stem cells specifically. [2]
A metabolic network is the complete set of metabolic and physical processes that determine the physiological and biochemical properties of a cell.As such, these networks comprise the chemical reactions of metabolism, the metabolic pathways, as well as the regulatory interactions that guide these reactions.
Each article at WikiPathways is dedicated to a particular pathway. Many types of molecular pathways are covered, including metabolic, [7] signaling, regulatory, etc. and the supported [8] species include human, mouse, zebrafish, fruit fly, C. elegans, yeast, rice and arabidopsis, [9] as well as bacteria and plant species.
This page is the template for the metabolic pathways template. This template should be used to illustrate the general 'shape' of metabolism within the cell . This template is part of the Metabolic Pathways task force .
In theoretical chemistry, an energy profile is a theoretical representation of a chemical reaction or process as a single energetic pathway as the reactants are transformed into products. This pathway runs along the reaction coordinate , which is a parametric curve that follows the pathway of the reaction and indicates its progress; thus ...
"The metabolic pathway of glycolysis converts glucose to pyruvate via a series of intermediate metabolites. Each chemical modification (red box) is performed by a different enzyme. Steps 1 and 3 consume ATP (blue) and steps 7 and 10 produce ATP (yellow). Since steps 6-10 occur twice per glucose molecule, this leads to a net production of energy."
In plant leaves, UTP—glucose-1-phosphate uridylyltransferase is a key part of the sucrose biosynthesis pathway, supplying Uridine diphosphate glucose to Sucrose-phosphate synthase which converts UDP-glucose and D-fructose 6-phosphate into sucrose-6-phosphate. [12]