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2. Melanoma - Wikipedia

   en.wikipedia.org/wiki/Melanoma

   Although controversial, sentinel lymph node biopsies and examination of the lymph nodes are also performed in patients to assess spread to the lymph nodes. A diagnosis of melanoma is supported by the presence of the S-100 protein marker. HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as ...

3. HMB-45 - Wikipedia

   en.wikipedia.org/wiki/HMB-45

   HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.

4. Sentinel lymph node - Wikipedia

   en.wikipedia.org/wiki/Sentinel_lymph_node

   The concept of the sentinel lymph node is important because of the advent of the sentinel lymph node biopsy technique, also known as a sentinel node procedure.This technique is used in the staging of certain types of cancer to see if they have spread to any lymph nodes, since lymph node metastasis is one of the most important prognostic signs.

5. TNM staging system - Wikipedia

   en.wikipedia.org/wiki/TNM_staging_system

   Nx: lymph nodes cannot be assessed; N0: no regional lymph nodes metastasis; N1: regional lymph node metastasis present; at some sites, tumor spread to closest or small number of regional lymph nodes; N2: tumor spread to an extent between N1 and N3 (N2 is not used at all sites) N3: tumor spread to more distant or numerous regional lymph nodes ...

6. Tumors of the hematopoietic and lymphoid tissues - Wikipedia

   en.wikipedia.org/wiki/Tumors_of_the...

   Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma Primary cutaneous acral CD8-positive T-cell lymphoma Primary cutaneous CD4-positive small/medium T-cell lymphoproliferative disorder Peripheral T-cell lymphoma, NOS Angioimmunoblastic T-cell lymphoma Follicular T-cell lymphoma

7. Lymphovascular invasion - Wikipedia

   en.wikipedia.org/wiki/Lymphovascular_invasion

   Lymphovascular invasion, especially in carcinomas, usually precedes spread to the lymph nodes that drain the tissue in which the tumour arose. Conversely, cancers with lymph node spread (known as a lymph node metastases), usually have lymphovascular invasion. Lymph node metastases usually precede secondary tumours, i.e. distant metastases.