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Most men and women know at least vaguely what Viagra does, but not everyone knows how it does it. ... Since 1998, the Pfizer-created drug sildenafil citrate has been a reliable treatment for the ...
For example, a small study of 20 people that looked into Viagra’s effect on refractory time found that a standard 100mg dose of sildenafil citrate reduced the average male post-intimacy recovery ...
Below, we’ve covered how you can take Viagra or generic sildenafil for optimal results, from the best time to take Viagra before intercourse to drug interactions and adverse effects that you ...
Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
In this study, eight out of the nine women required 50 mg of sildenafil while the 9th woman required 100 mg of sildenafil. Another option for women who have SSRI-induced anorgasmia is the use of vardenafil. Vardenafil is a type 5 phosphodiesterase (PDE5) inhibitor that facilitates muscle relaxation and improves penile erection in men.