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The physiological blood-flow response largely decides the temporal sensitivity, how well neurons that are active can be measured in BOLD fMRI. The basic time resolution parameter is the sampling rate, or TR, which dictates how often a particular brain slice is excited and allowed to lose its magnetization. TRs could vary from the very short ...
The slice preparation or brain slice is a laboratory technique in electrophysiology that allows the study of neurons from various brain regions in isolation from the rest of the brain, in an ex-vivo condition. Brain tissue is initially sliced via a tissue slicer then immersed in artificial cerebrospinal fluid (aCSF) for stimulation and/or ...
A voxel is a three-dimensional rectangular cuboid, whose dimensions are set by the slice thickness, the area of a slice, and the grid imposed on the slice by the scanning process. Full-brain studies use larger voxels, while those that focus on specific regions of interest typically use smaller sizes.
A 2-D model of cortical sensory homunculus. A cortical homunculus (from Latin homunculus 'little man, miniature human' [1] [2]) is a distorted representation of the human body, based on a neurological "map" of the areas and portions of the human brain dedicated to processing motor functions, and/ or sensory functions, for different parts of the body.
Autoradiography of a coronal brain slice, taken from an embryonal rat. GAD67-binding marker is highly expressed in the subventricular zone.. An autoradiograph is an image on an X-ray film or nuclear emulsion produced by the pattern of decay emissions (e.g., beta particles or gamma rays) from a distribution of a radioactive substance.
It is believed to play a role in some cases of human epilepsy. [7] [8]It has also been implicated in working memory [9] and drug addiction. [10]It has been suggested that the dorsal subiculum is involved in spatial relations, and the ventral subiculum regulates the hypothalamic-pituitary-adrenal axis.
Stained brain slice images which include the "putamen" at the BrainMaps project "Anatomy diagram: 13048.000-2". Roche Lexicon - illustrated navigator. Elsevier. Archived from the original on 2012-07-22. Diagram at uni-tuebingen.de; Atlas image: eye_38 at the University of Michigan Health System – "The Visual Pathway from Below"
Artificial cerebrospinal fluid (aCSF) is a buffer solution prepared with a composition representative of cerebrospinal fluid that is used experimentally to immerse isolated brains, brain slices, or exposed brain regions to supply oxygen, maintain osmolarity, and to buffer pH at biological levels.