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The anterior pituitary (also called the adenohypophysis or pars anterior) is a major organ of the endocrine system.The anterior pituitary is the glandular, anterior lobe that together with the (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis) which, in humans, is located at the base of the brain, protruding off the bottom of the hypothalamus.
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [ 2 ] and regulates the development, growth, pubertal maturation , and reproductive processes of the body.
Genes for human growth hormone, known as growth hormone 1 (somatotropin; pituitary growth hormone) and growth hormone 2 (placental growth hormone; growth hormone variant), are localized in the q22-24 region of chromosome 17 [7] [8] and are closely related to human chorionic somatomammotropin (also known as placental lactogen) genes.
Release of FSH and LH from anterior pituitary. 34 Growth Hormone-Releasing Hormone: GHRH Peptide: hypothalamus: GHRH receptor → IP 3: pituitary gland: Release GH from anterior pituitary: 35 Hepcidin: HAMP Peptide: liver: ferroportin: inhibits iron export from cells 36 Human Chorionic Gonadotropin: HCG Peptide: placenta: syncytiotrophoblast ...
For example, a child who has a profound deficiency in growth hormone (especially if they are a cancer survivor with damage to the pituitary gland) may need to continue taking HGH as an adult ...
Growth hormone is made in the anterior pituitary gland, released into the bloodstream, and then stimulates the liver to produce IGF-1. IGF-1 then stimulates systemic body growth , and has growth -promoting effects on almost every cell in the body, especially skeletal muscle , cartilage , bone , liver , kidney , nerve , skin , hematopoietic ...
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