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A cranial nerve nucleus is a collection of neurons (gray matter) in the brain stem that is associated with one or more of the cranial nerves. Axons carrying information to and from the cranial nerves form a synapse first at these nuclei .
Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs.Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck, including the special senses of vision, taste, smell, and hearing.
The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla, and into the upper cervical spinal cord. The nucleus is divided into three parts, from rostral to caudal (top to bottom in humans): The mesencephalic nucleus; The principal sensory nucleus
Basal ganglia: striatum (caudate and putamen), pallidum (globus pallidus, medial and lateral), substantia nigra, subthalamic nucleus; Cranial nerve nuclei; Ventromedial nucleus of the hypothalamus: "The ventromedial hypothalamus (VMH) is a distinct morphological nucleus involved in feeding, fear, thermoregulation, and sexual activity."
The pontine tegmentum contains nuclei of the cranial nerves (trigeminal (5th), abducens (6th), facial (7th), and vestibulocochlear (8th) and their associated fibre tracts. . The dorsal pons also contains the reticulotegmental nucleus, the mesopontine cholinergic system comprising the pedunculopontine nucleus and the laterodorsal tegmental nucle
The abducens nucleus is the originating nucleus from which the abducens nerve (VI) emerges—a cranial nerve nucleus. This nucleus is located beneath the fourth ventricle in the caudal portion of the pons near the midline, [ 1 ] medial to the sulcus limitans .
The mesencephalic nucleus of trigeminal nerve is one of the sensory nuclei of the trigeminal nerve (cranial nerve V). It is located in the brainstem. It receives proprioceptive sensory information from the muscles of mastication and other muscles of the head and neck. It is involved in processing information about the position of the jaw/teeth.
Ten of the twelve pairs of cranial nerves either target or are sourced from the brainstem nuclei. [14]: 725 The nuclei of the oculomotor nerve (III) and trochlear nerve (IV) are located in the midbrain. The nuclei of the trigeminal nerve (V), abducens nerve (VI), facial nerve (VII) and vestibulocochlear nerve (VIII) are located in the pons.