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Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
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Problem solving is the process of achieving a goal by overcoming obstacles, a frequent part of most activities. Problems in need of solutions range from simple personal tasks (e.g. how to turn on an appliance) to complex issues in business and technical fields.
The problem to determine all positive integers such that the concatenation of and in base uses at most distinct characters for and fixed [citation needed] and many other problems in the coding theory are also the unsolved problems in mathematics.
Modal analysis using FEM — solution of eigenvalue problems to find natural vibrations; Céa's lemma — solution in the finite-element space is an almost best approximation in that space of the true solution; Patch test (finite elements) — simple test for the quality of a finite element
Wicked problem – Problem that is difficult or impossible to solve; World Community Grid – BOINC based volunteer computing project to aid scientific research; WorldRiskReport – Annual cooperation report on global disaster risks; World-systems theory – Approach emphasizing the world-system as the primary unit of social analysis
Binding problem: How exactly is it that objects, background, and abstract or emotional features are combined into a single experience? What is the neural basis of self ? Quantum mind : Does quantum mechanical phenomena, such as entanglement and superposition , play an important part in the brain's function and can it explain critical aspects of ...
The halting problem is a decision problem about properties of computer programs on a fixed Turing-complete model of computation, i.e., all programs that can be written in some given programming language that is general enough to be equivalent to a Turing machine. The problem is to determine, given a program and an input to the program, whether ...