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The nucleophilic lysine residue is commonly targeted site in protein bioconjugation, typically through amine-reactive N-hydroxysuccinimidyl (NHS) esters. [3] To obtain optimal number of deprotonated lysine residues, the pH of the aqueous solution must be below the pKa of the lysine ammonium group, which is around 10.5, so the typical pH of the reaction is about 8 and 9.
According to Mikhail B. Sevryuk, in the January 2006 issue of the Bulletin of the American Mathematical Society, "The number of papers and books included in the Mathematical Reviews (MR) database since 1940 (the first year of operation of MR) is now more than 1.9 million, and more than 75 thousand items are added to the database each year. The ...
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, with a half-life of only 771.9(9) ms and 12 B with a half-life of 20.20(2) ms. All other isotopes have half-lives shorter than 17.35 ms. Those isotopes with mass below 10 decay into helium (via short-lived isotopes of beryllium for 7 B and 9 B) while those with mass above 11 mostly become carbon.
The seventh member of group 18 is oganesson, an unstable synthetic element whose chemistry is still uncertain because only five very short-lived atoms (t 1/2 = 0.69 ms) have ever been synthesized (as of 2020 [3]).
This page provides lists of best-selling books and book series to date and in any language. "Best-selling" refers to the estimated number of copies sold of each book, rather than the number of books printed or currently owned. Comics and textbooks are not included in this list. The books are listed according to the highest sales estimate as ...
Allow user to press shortcuts one key at a time: ⇧ Shift press 5 times: ⇧ Shift 5 times [28] Hear beep when -lock key pressed: Numlock hold 5 seconds: Stop/slow repeating characters when key is pressed: Right Shift hold 8 seconds: ⇧ Shift hold for 8 seconds [29] [30] [31] Inverse (Reverse Colors) Mode Left Alt+Left Shift+PrtScn: ⌘ Cmd+ ...
A typical 105-key computer keyboard, consisting of sections with different types of keys. A computer keyboard consists of alphanumeric or character keys for typing, modifier keys for altering the functions of other keys, [1] navigation keys for moving the text cursor on the screen, function keys and system command keys—such as Esc and Break—for special actions, and often a numeric keypad ...