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Ciprofloxacin/dexamethasone, sold under the brand name Ciprodex among others, is an antibiotic/steroid fixed-dose combination medication used for the treatment of ear ...
Ciprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C 17 H 18 FN 3 O 3 and its molecular weight is 331.4 g/mol. It is a faintly yellowish to light yellow crystalline substance. [68] Ciprofloxacin hydrochloride is the monohydrochloride monohydrate salt of ciprofloxacin ...
Antibiotic ear drops are much faster at killing the bacteria. [19] Ear drops work faster since the medication directly goes to the site of infection whereas oral antibiotics enter the bloodstream first. [19] Some commonly used antibiotics include: Ciprodex ear drops containing ciprofloxacin and dexamethasone [20]
A/B otic drops is indicated for ear pain caused by otitis media. It is used every 2–3 hours as needed for pain. [2] A/B otic drops is also indicated for the removal of excessive or impacted cerumen. To clear cerumen, it is used 3 times a day for 2–3 days. [2]
Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
The overall frequency of fluoroquinolone-associated Achilles tendon rupture in patients treated with ciprofloxacin or levofloxacin has been estimated at 17 per 100,000 treatments. [ 21 ] [ 22 ] Risk is substantially elevated in the elderly and in those with recent exposure to topical or systemic corticosteroid therapy.
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Ear drops are the mainstay of treatment for external otitis. Some contain antibiotics, either antibacterial or antifungal, and others are simply designed to mildly acidify the ear canal environment to discourage bacterial growth. Some prescription drops also contain anti-inflammatory steroids, which help to resolve swelling and itching.