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Concentric hypertrophy is a hypertrophic growth of a hollow organ without overall enlargement, [1] in which the walls of the organ are thickened and its capacity or volume is diminished. Sarcomeres are added in parallel, as for example occurs in hypertrophic cardiomyopathy .
Concentric hypertrophy results from various stressors to the heart including hypertension, congenital heart defects (such as Tetralogy of Fallot), valvular defects (aortic coarction or stenosis), and primary defects of the myocardium which directly cause hypertrophy (hypertrophic cardiomyopathy). The underlying commonality in these disease ...
The concentric hypertrophy is due to the increased left ventricular pressure overload associated with AI, while the eccentric hypertrophy is due to volume overload caused by the regurgitant fraction. [15] Physiologically, in individuals with a normally functioning aortic valve, the valve is only open when the pressure in the left ventricle is ...
Ventricular remodeling may include ventricular hypertrophy, ventricular dilation, cardiomegaly, and other changes. It is an aspect of cardiomyopathy, of which there are many types. Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload. [6]
Pressure overload may affect any of the four chambers of the heart, though the term is most commonly applied to one of the two ventricles. Chronic pressure overload leads to concentric hypertrophy of the cardiac muscle, which can in turn lead to heart failure, myocardial ischaemia or, in extreme cases, outflow obstruction. [1]
Your heart valves control the way blood flows in and out of your heart and through the four chambers of your heart. Valvular heart disease occurs when any of the valves in your heart are damaged.