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However, the condition may arise anywhere minor salivary glands are located. [nb 1] It has also been occasionally reported to involve the major salivary glands. [2] [3] It may be present only on one side, or both sides. [1] The lesion typically is 1–4 cm in diameter. [4] Initially, the lesion is a tender, erythematous (red) swelling. Later ...
Pleomorphic adenomas may recur after a very long time from primary surgery, on average over 7–10 years and up to 24 years. [10] [11] Survival rates due to malignancy depends on the patient and extent of disease. [4] A 10-year survival ranges from 32-83%. [4] Of all cancers, salivary gland tumors account for only 1%. [4]
Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases.
Sialoendoscopy is a minimally invasive technique that allows for salivary gland surgery for the safe and effective treatment of obstructive salivary gland disorders and other conditions of the salivary glands. During sialoendoscopy a small endoscope is placed into the salivary glands through the salivary ducts that empty into the mouth.
Treatment options may include surgery, radiation, and chemotherapy. Icotinib has been temporarily effective at treating salivary gland-like carcinoma of the lung but loses efficiency after three months.
After a histologic diagnosis has been established and tumor extent determined, such as with the use of PET-CT, [94] the selection of appropriate treatment for a specific cancer depends on a complex array of variables, including tumor site, relative morbidity of various treatment options, concomitant health problems, social and logistic factors ...
Pleomorphic adenoma (or benign mixed tumor) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland.
Salivary gland dysfunction refers to either xerostomia (the symptom of dry mouth) or salivary gland hypofunction (reduced production of saliva); it is associated with significant impairment of quality of life. [34] Following radiotherapy of the head and neck region, salivary gland dysfunction is a predictable side-effect. [34]