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  2. Double-stranded RNA viruses - Wikipedia

    en.wikipedia.org/wiki/Double-stranded_RNA_viruses

    Double-stranded RNA viruses (dsRNA viruses) are a polyphyletic group of viruses that have double-stranded genomes made of ribonucleic acid.The double-stranded genome is used as a template by the viral RNA-dependent RNA polymerase (RdRp) to transcribe a positive-strand RNA functioning as messenger RNA (mRNA) for the host cell's ribosomes, which translate it into viral proteins.

  3. Gammaretrovirus - Wikipedia

    en.wikipedia.org/wiki/Gammaretrovirus

    The virus is now referred to as a provirus, which means the gammaretrovirus DNA has integrated into the host cell genome and is now the template for the formation of viral mRNA and genomic RNA. Double-stranded DNA is transcribed by Pol II and will produce both spliced and unspliced RNA strands, these spliced RNA strands will leave the host cell ...

  4. Double-stranded RNA - Wikipedia

    en.wikipedia.org/wiki/Double-stranded_RNA

    It is similar to DNA but with the replacement of thymine by uracil and the adding of one oxygen atom. [1] Despite the structural similarities, much less is known about dsRNA. [2] They form the genetic material of some viruses (double-stranded RNA viruses). dsRNA, such as viral RNA or siRNA, can trigger RNA interference in eukaryotes, as well as ...

  5. Rotavirus - Wikipedia

    en.wikipedia.org/wiki/Rotavirus

    The eleven dsRNA strands remain within the protection of the two protein shells and the viral RNA-dependent RNA polymerase creates mRNA transcripts of the double-stranded viral genome. By remaining in the core, the viral RNA evades innate host immune responses including RNA interference that are triggered by the presence of double-stranded RNA ...

  6. RNA virus - Wikipedia

    en.wikipedia.org/wiki/RNA_virus

    This means that the virus must bring along with it the enzyme RNA replicase. The positive-sense RNA molecule then acts as viral mRNA, which is translated into proteins by the host ribosomes. Retroviruses (Group VI) have a single-stranded RNA genome but, in general, are not considered RNA viruses because they use DNA intermediates to replicate.

  7. Human betaherpesvirus 5 - Wikipedia

    en.wikipedia.org/wiki/Human_betaherpesvirus_5

    CMV is a double-stranded DNA virus. [5] Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. [4] HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn ...

  8. RNA therapeutics - Wikipedia

    en.wikipedia.org/wiki/RNA_Therapeutics

    The main types of RNA therapeutics are those based on messenger RNA (mRNA), antisense RNA (asRNA), RNA interference (RNAi), and RNA aptamers. Of the four types, mRNA-based therapy is the only type which is based on triggering synthesis of proteins within cells, making it particularly useful in vaccine development. [ 3 ]

  9. Hepatitis D - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_D

    The RNA polymerases treat the RNA genome as double-stranded DNA due to the folded rod-like structure it is in. Three forms of RNA are made; circular genomic RNA, circular complementary antigenomic RNA, and a linear polyadenylated antigenomic RNA, which is the mRNA containing the open reading frame for the HDAg.

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