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Dr. Narayanan says that bone pain can also be a sign of prostate cancer recurrence in patients who have already had the disease. The link between prostate cancer and bone pain may be a surprising one.
Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [ 91 ] Prostate cancer is rare in those under 40 years old, [ 92 ] and most cases occur in those over 60 years, [ 2 ] with the average person diagnosed at 67. [ 93 ]
Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of metastatic spinal cord compression is ...
The list below details the likelihood of a cancer, if in a stage of advanced metastasis, to have spread to bone at time of death: [26] Breast: 65-75%; Prostate: 65-75%; Thyroid: 60%; Kidney: 20-25%; Lung: 30-40%; Given the high incidence of breast, lung and prostate cancer, these patients account for > 80% of patients with bone metastases. [15]
There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.
Bisphosphonates such as zoledronic acid have been shown to delay skeletal complications such as fractures or the need for radiation therapy in patients with hormone-refractory metastatic prostate cancer. [84] Xofigo is a new alpha-emitting pharmaceutical targeting bone metastasis. Phase II testing shows prolonged patient survival times, reduced ...
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