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The underlying mechanism generally involves problems with the pituitary gland. [2] Some cases are associated with a lack of other pituitary hormones, in which case it is known as combined pituitary hormone deficiency. [4] Diagnosis involves blood tests to measure growth hormone levels. [2]
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. GH also stimulates production of insulin-like growth factor 1 (IGF-1) and increases ...
Hypophysitis, inflammation of the pituitary gland. Autoimmune hypophysitis (or lymphocytic hypophysitis), inflammation of the pituitary gland due to autoimmunity. Nelson's syndrome, may occur after surgical removal of both adrenal glands, an out-dated method of treating Cushing's disease. Pituitary tumour, a tumor of the pituitary gland.
Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical ...
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1][2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3] If there is decreased secretion of most or all pituitary ...
The excess of growth hormone that brings about gigantism is virtually always caused by pituitary growths . [7] These adenomas are on the anterior pituitary gland. They can also cause overproduction of GH's hypothalamic precursor known as growth hormone releasing hormone (GHRH). [10] As a result of the excessive amounts of growth hormone ...
Acromegaly is a syndrome caused by the anterior pituitary gland producing excess growth hormone (GH). [42] A number of disorders may increase the pituitary's GH output, although most commonly it involves a tumor called pituitary adenoma, derived from a distinct type of cell (somatotrophs).
Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin-C) production in response to growth hormone (GH; hGH; somatotropin). [6] It is usually caused by inherited growth hormone ...