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2. Migraine - Wikipedia

   en.wikipedia.org/wiki/Migraine

   Migraine; Woman during a migraine attack: Specialty: Neurology: Symptoms: ... Sensitization of trigeminal pathways is a key pathophysiological phenomenon in migraine ...

3. Trigeminovascular system - Wikipedia

   en.wikipedia.org/wiki/Trigeminovascular_system

   Hence, the TVS has provided a template for migraine pathophysiology and target for drug discovery. The history of some discoveries re the TV System are summarised in Ashina, et al. [13] The Brain Prize for 2021 was awarded to 4 investigators studying the trigeminovascular system and its implications for migraine pathophysiology and treatments.

4. ICHD classification and diagnosis of migraine - Wikipedia

   en.wikipedia.org/wiki/ICHD_classification_and...

   The patient experiences typical migraine with aura headache either preceded or accompanied with one-sided, reversible limb weakness and/or sensory difficulties and/or speech difficulties. FHM is associated with ion channel mutations. When no close family show symptoms, it is known as sporadic hemiplegic migraine.

5. UVA pain research suggests new ways to manage migraine ... - AOL

   www.aol.com/uva-pain-research-suggests-ways...

   By targeting progesterone receptors, researchers and clinicians can potentially modulate these pathways to mitigate migraine and other chronic pain conditions. “However, further research is ...

6. Genetics of migraine - Wikipedia

   en.wikipedia.org/wiki/Genetics_of_migraine

   Finally, migraine may be a component of imperfect central nervous system design. Evidence has suggested a dysfunction of pain-inhibitory pathways in migraine and discordant interaction between the ancient brain stem design and the more evolved neocortex.

7. Calcitonin gene-related peptide - Wikipedia

   en.wikipedia.org/wiki/Calcitonin_gene-related...

   It interacts with the CGRP protein, whose expression is related to migraine attacks. It may be administered monthly or every three months, giving options for users. Trials have shown a reduction of greater than 50% of migraine days for those who responded. There were few significant side effects during trials, most related to injection site ...