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Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [10] [4] It is used as a method of birth control and as a part of menopausal hormone therapy.
Hormonal depot injections of estradiol can last anywhere from one week to over one month. [7] Medroxyprogesterone acetate is available as a depot injection which is injected once every three months to provide continuous hormonal contraception and releases for up to nine months after injection. [8]
[2] [3] As opposed to combined injectable contraceptives, they contain only a progestogen without an estrogen, and include two progestin preparations: [2] [3] Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [ 4 ] – 150 mg ( intramuscularly ) or 104 mg ( subcutaneously ) every 3 months [ 3 ]
[48] [50] [59] A 2016 systematic review found based on limited evidence from 6 studies that hormonal birth control, including combined birth control pills, depot medroxyprogesterone acetate, and levonorgestrel-containing intrauterine devices, was not associated with worse outcomes compared to non-use in women with depressive or bipolar ...
Hormonal contraceptives can come in multiple forms including injectables. Depot medroxyprogesterone acetate (DMPA), a progestin-only injectable, has been found to cause amenorrhea (cessation of menstruation); however, the irregular bleeding pattern returns to normal over time. [15] [16] DMPA has also been associated with weight gain. [16]
CICs are different from progestogen-only injectable contraceptives (POICs), such as depot medroxyprogesterone acetate (DMPA; brand names Depo-Provera, Depo-SubQ Provera 104) and norethisterone enantate (NETE; brand name Noristerat), which are not combined with an estrogen and are given once every two to three months instead of once a month. [2]
Cyproterone acetate (Androcur, Cyprostat, Diane, Diane-35) Hydroxyprogesterone caproate (Proluton, Proluton Depot, Makena; Delalutin) Medroxyprogesterone acetate (Depo-Provera, Provera) Megestrol acetate (Megace) And the following minor progestogen esters have been marketed: Acetomepregenol (mepregenol diacete; Diamol) Anagestone acetate ...
Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. [2] It contains estradiol cypionate (EC), an estrogen, and medroxyprogesterone acetate (MPA), a progestin. [2] It is recommended for short-term use and is given once a month by injection into ...