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Sometimes hair has a tendency to curl after regrowth, resulting in "chemo curls." Severe hair loss occurs most often with drugs such as doxorubicin, daunorubicin, paclitaxel, docetaxel, cyclophosphamide, ifosfamide and etoposide. Permanent thinning or hair loss can result from some standard chemotherapy regimens. [101]
Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. [13] It is also being studied for other types of cancer. [13] It has been used for Albright syndrome. [14] Tamoxifen is typically taken daily by mouth for five years for breast cancer. [14]
Tension or strain on the hair damages the follicle, impacting the ability for blood flow and nutrients to reach it and can result in permanent hair loss, says Dr. Mirmirani.
Cancer Medications. Hair loss is a well-known side effect of many chemotherapy drugs used to treat certain forms of cancer. Similar to other toxins that cause hair loss, hair loss from cancer ...
Tamoxifen is a pure antiestrogenic trans-isomer and has differential actions at estrogen target tissues throughout the body. Tamoxifen is selectively antiestrogenic in the breast but estrogen-like in bones and endometrial cancer. [24] Tamoxifen undergo phase I metabolism in the liver by microsomal cytochrome P450 (CYP) enzymes.
Female pattern hair loss (FPHL). This is also called female pattern baldness, androgenetic alopecia, or androgenic alopecia (AGA). It’s the most common cause of hair loss in women. FPHL usually ...
While the FDA hasn’t approved oral minoxidil for hair loss, clinical trials have shown it’s quite effective for hair growth at various doses (0.25 to 2.5 mg daily). Spironolactone .
Dutasteride is also used in the treatment of male pattern hair loss and appears to have better effectiveness than finasteride for the condition. [27] [28] [29] While used off-label for male pattern hair loss in most of the world, dutasteride is specifically approved for this indication in South Korea and Japan. [30] [31]