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Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [5] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [2] With AS, eye and bowel problems—as well as back pain—may occur. [2]
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
Ankylosing spondylitis is a genetic disease with identifiable marks, tends to start showing signs in adolescence or young adulthood, is more likely to affect the lumbar spine, and affects organs. DISH has no indication of a genetic link, is primarily thoracic and does not affect organs other than the lungs, and only indirectly due to the fusion ...
Among the genetic factors that may influence ankylosing spondylitis, the HLA-B27 gene accounts for about thirty percent of the overall genetic risk, per the National Library of Medicine. The ...
Microscopically visible ileal inflammation is seen in about 50% of people with spondyloarthritis and ankylosing spondylitis during ileocolonoscopy. [11] [4] There seems to be an immunological connection between the gut inflammation observed in Crohn's disease and ankylosing spondylitis. [12]
Enthesopathy of the pelvis likely due to ankylosing spondylitis Enthesopathy can occur at the shoulder, elbow, wrist, carpus , hip, knee, ankle, tarsus , or heel bone , among other regions. Enthesopathies may take the form of spondyloarthropathies (joint diseases of the spine) such as ankylosing spondylitis , or psoriatic arthritis , plantar ...
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