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Sjögren's syndrome (SS) is the third-most common rheumatic autoimmune disorder, behind rheumatoid arthritis and systemic lupus erythematosus. [19] There are no geographical differences in the rates of SS. [97] Sjögren's syndrome has been reported in all areas of the world, although regional rates have not been well studied. [97] [98]
Paraneoplastic syndrome, Guillain-Barré syndrome, diabetes, amyloidosis, Sjogren's syndrome, and Morvan syndrome. Autoimmune autonomic ganglionopathy is a type of immune-mediated autonomic failure that is associated with antibodies against the ganglionic nicotinic acetylcholine receptor present in sympathetic , parasympathetic , and enteric ...
Sjögren–Larsson syndrome is a rare autosomal recessive form of ichthyosis with neurological symptoms. [ 1 ] : 485 [ 2 ] : 564 [ 3 ] It can be identified by a triad of medical disorders. The first is ichthyosis , which is a buildup of skin to form a scale-like covering that causes dry skin and other problems.
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In Sjogren's sensory neuronopathy, vibratory and proprioceptive sensations are profoundly affected, leading to a severe ataxia. [5] Sensory neuronopathy is thought to involve 40% of neuropathies in Sjogren's syndrome and 5% of all cases of Sjogren's overall, it is usually subacute in onset.
Guillain-Barré syndrome: Peripheral nerves Various, including anti-GM1, anti-GD1a Confirmed 1-2 per 100,000 [60] Hashimoto's encephalopathy: Brain Anti-thyroid (TPO, Tg) Probable Rare [61] Idiopathic inflammatory demyelinating diseases: Central nervous system Varies Probable Varies by specific disease [62] Lambert–Eaton myasthenic syndrome
Immunofluorescence pattern of SS-A and SS-B antibodies. Produced using serum from a patient on HEp-20-10 cells with a FITC conjugate. Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA, anti–SS-A/Ro, and anti-Ro/SS-A) are a type of anti-nuclear autoantibodies that are associated with ...
Parotid gland swellings can also be due to benign lymphoepithelial lesions [clarification needed] caused by Mikulicz disease and Sjögren syndrome. Swelling of the parotid gland may also indicate the eating disorder bulimia nervosa , creating the look of a heavy jaw line.