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Doxycycline is also used as a prophylactic treatment for infection by Bacillus anthracis and is effective against Yersinia pestis, the infectious agent of bubonic plague. It is also used for malaria treatment and prophylaxis, as well as treating elephantitis filariasis. [10]
Plague (Yersinia pestis): Has historically been used as the first-line treatment. However streptomycin is approved for this purpose only by the US Food and Drug Administration. [medical citation needed] In veterinary medicine, streptomycin is the first-line antibiotic for use against gram negative bacteria in large animals (horses, cattle ...
Yersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both Yersinia enterocolitica and Yersinia pseudotuberculosis, the pathogen from which Y. pestis evolved [1] [2] and responsible for the Far East scarlet-like fever.
The following is a list of antibiotics. ... Effective for gram-positive, gram-negative, anaerobic, and against multi-antibiotic resistant bacteria ...
Within the genus Yersinia, only Y. pestis, Y. pseudotuberculosis, and certain strains of Y. enterocolitica are pathogenic for humans and certain animals. The other species are environmental in origin. [5] Y. enterocolitica strains can be identified through the use of stool samples being grown on MacConkey plates and Yersinia Selective Agar.
The product of this gene, LcrV protein, also regulates the secretion of YopD through the type III translocon, and itself acts as a protective "V" antigen for Yersinia pestis, the causative agent of plague. [4] [5] A homologue of the Y. pestis LcrV protein, PcrV, has been found in Pseudomonas aeruginosa, an opportunistic pathogen.
Gemifloxacin mesylate, sold under the brand name Factive among others, is a broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
S. griseus and its related strains have recently been shown to be alkaliphilic, i.e., they grow best at alkaline pH values. Although these organisms grow in a wide pH range (from 5 to 11), they show a growth optimum at pH 9. [10] They produce grey spore masses and grey-yellow reverse pigments when they grow as colonies. [2]